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Animal RNAi Studies
Animal RNAi studies are experimental studies where RNA interference (RNAi) is used to specifically target and knockdown the expression of genes in animal models. RNAi is a powerful tool for studying gene function, as it allows for the rapid and specific inhibition of gene expression in cells and organisms. Animal RNAi studies typically involve the…
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Targeting Protein of Interest
Targeting a protein of interest is a common strategy used in drug discovery and development to develop therapeutics that specifically modulate the activity or expression of the protein of interest. There are several approaches to target a protein of interest, including small molecule inhibitors, monoclonal antibodies, RNA-based therapies, and gene editing. Small molecule inhibitors are…
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shRNA-Expressing Constructs
shRNA-expressing constructs are genetic constructs that encode short hairpin RNAs (shRNAs) for the purpose of inducing RNA interference (RNAi) in cells. These constructs are widely used in research to study gene function and to develop new therapies for a variety of diseases. It typically consist of a promoter, a shRNA sequence, and a termination sequence.…
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RNAi Stable Cell Lines
RNAi stable cell lines refer to cell lines that have been genetically modified to stably express short hairpin RNAs (shRNAs) or other RNA-based molecules that induce RNA interference (RNAi). These cell lines are used in research to study gene function and to develop new therapies for a variety of diseases. RNAi stable cell lines are…
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Transient RNAi
Transient RNAi refers to a type of RNA interference (RNAi) that results in the temporary inhibition of gene expression. RNAi is a natural biological process in which RNA molecules, such as small interfering RNAs (siRNAs), bind to specific messenger RNA (mRNA) molecules and prevent them from being translated into protein. Transient RNAi can be achieved…
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Gene Silencing Services
Gene silencing services refer to the development and production of RNA-based molecules that can inhibit the expression of specific genes. These services are used in research and drug development to study the function of genes and to develop new therapies for a variety of diseases. There are several types of RNA-based molecules that can be…
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Liposome Encapsulation
Liposome encapsulation refers to the process of enclosing a drug or other therapeutic agent within a lipid bilayer structure called a liposome. Liposomes are spherical structures composed of a phospholipid bilayer that can be used to deliver drugs to specific cells or tissues in the body. Liposomes can be used to encapsulate a wide variety…
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Protein/DNA/RNA
Proteins, DNA, and RNA are macromolecules that play important roles in biological processes. Proteins are large, complex molecules composed of amino acids that perform a wide variety of functions in the body. They can act as enzymes, which catalyze chemical reactions, or as structural components of cells and tissues. Proteins also play a role in…
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Therapeutic Small RNA Development
Therapeutic small RNA development refers to the process of developing small RNA molecules for use as therapeutic agents in the treatment of various diseases. Small RNAs are non-coding RNA molecules that play a role in regulating gene expression and can be used to target specific genes and pathways involved in disease. There are several types…
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Tox Studies
Toxicity studies, also known as toxicology studies, are an important component of drug development and refer to experiments or studies conducted to evaluate the potential adverse effects of a drug candidate on living organisms. These studies are designed to assess the safety of a drug candidate and to determine the dosage levels at which it…