Altogen Labs standard research services:

• RNAi services: synthesis, chem modification, tissue targeting
• Liposome formulation, siRNA liposome encapsulation
• ELISA and cell-based assay development
• Pharmaceuticals testing in vitro and in vivo, IC50 assays
• Over 50 validated xenograft models
• Stem cells isolation, characterization, and cell bank services
• Generation of stable cell lines (protein overexpression) in 28 days
• Generation of stable RNAi cell lines targeting gene of interest
• Genome-wide library screening (small molecule, siRNA, miRNA)
• In Vitro siRNA test (100+ cell lines/primary cultures available)
• DNA and RNA isolation and purification
• Cell-based assays: cytotoxicity, apoptosis, cell cycle arrest, etc
• Protein services
• Xenograft animal models CRO service
• Transient and stable transfection services
• siRNA, shRNA, miRNA design and synthesis
• Liposome encapsulation service of RNA, DNA, and proteins
• Oligonucleotide (siRNA) chemical modification: in vivo
• Endotoxin and RNase contamination testing
• Quantitation of gene silencing by qRT-PCR and Western Blot
• GLP-compliant cell bank construction and cryopreservation
• Custom reporter gene assays
• Devolopment of in vivo transfection kits and reagents
• In Vivo siRNA delivery and tissue targeted siRNA development