Altogen Services provides life science research services to pharmaceutical, biotechnology, and academic institutions worldwide, offering a complete solution for RNAi (gene silencing) projects, generation of stable cell lines, cloning, protein expression, reporter assay development, cell culture, transient and stable transfection, functional library screening (siRNA and microRNA), and various other biology and pharmacology services.

Altogen Services research and development department is located in Austin, Texas and is a wholly owned subsidiary of Altogen Biosystems located in Las Vegas, Nevada.

Our scientists bring years of extensive experience and expertise to virtually all types of pre-clinical studies, cell and molecular biology, and RNAi. Altogen Services offers a wide range of custom research services to meet the unique needs of our clients. Our Technical Support and QC teams ensure and support our high-quality products and services.

Altogen Services provides instant online quotation (techserv@altogen.com), comprehensive service packages, and highly competitive prices.

Our Standard Research Services include:

• RNAi Services, Gene targeting
• Liposome formulation, Custom liposome encapsulation
• Tissue culture services, Cell-based assay development
• Pharmaceuticals testing in vitro and in vivo
• PCR cloning and vector construction
• Stem cells isolation and characterization
• Generation of stable cell lines (protein overexpression)
• Generation of stable RNAi cell lines (stably expressing shRNA targeting gene of interest)
• Genome-wide library screening (small molecule, siRNA, miRNA)
• In Vitro Functional testing of siRNA gene silencing efficiency (50+ cell lines/primary cultures available)
• DNA and RNA isolation and purification
• Cell-based assays: cytotoxicity, apoptosis, cell cycle arrest, etc
• Protein services
• Transient and stable transfection services
• siRNA, shRNA, miRNA design and synthesis
• Oligonucleotide (siRNA, miRNA) chemical modification to enhance stability in vivo
• Endotoxin and RNase contamination testing
• Quantitation of siRNA/shRNA gene silencing effect by qRT-PCR and Western Blot
• Transfection reagent optimization and development
• Cryopreservation service
• Custom reporter gene assays

Once we know the details of your project, we can provide you with an immediate price quote (contact e-mail: techserv@altogen.com). Please note that experimental details will help us to provide an accurate quote and timeline estimate.